Split dosing Reta vs once a week

I've had issues with it as well. I keep trying to find the sweet spot and its just not lining up for me. I actually to split week dosing (.75 and .75mg) for Monday / Thursday. It's only been one week, but I honestly feel better. Sides do seem slightly improved, but one week is just too early to tell. I would say go for the split dosing and see how you feel. Nothing bad is going to happen. End of the day we're all researchers. Maybe someone else around here can reply who has been doing the split dosing longer than I have.

I do 1mg a week split into 3 doses EOD. So each dose is technically .333mcg. An easier way to dose would be 300mcg/300mcg/400mcg, etc. I don't do this because it's too much work.

I know the science says 2mg is "the" dose to start on, but I started at 1mg and am leaving it there.

Three doses! First I've seen of this. Did you try one dose or two doses a week first?

I wouldn't really put the "science" label on 2mg to start. That's just what the clinical trials started at because they are testing. I think and this is 100% personal opinion, but starter dose to assess tolerance for me would be .5mg. For a lean person built like a swimmer (such as myself), 2mg was really difficult on my body and I had to move back down to 1.25mg.

Honestly 1mg split three ways sounds like more work than I’d ever keep up with lol, but if it’s working I don’t see a reason to move up either. I think people treat these doses like levels they’re supposed to unlock instead of stopping where they’re getting results. Are you splitting mainly to avoid sides, or does the suppression actually feel more consistent that way?

I split mine mostly because the day after my shot was becoming a complete write-off. Went from 2mg Sunday to 1mg Sunday / 1mg Thursday. Definitely smoother for me. I don’t get that brick wall feeling anymore and the appetite suppression still holds. Only downside is remembering two shot days instead of one.

Tried splitting for about a month and ended up going back to once weekly. The sides were a little easier, but I felt like I was thinking about food more often. Could have been in my head, but one dose just works better for me. I moved the shot to Friday night so the rough part lands on the weekend.