Bloodwork & Biomarkers

Peptide
Bloodwork Guide

Know your baseline. Track the markers that fit your protocol. Bring better questions—and real data—to your clinician.

Baseline checklist Protocol-specific panels Suggested timing

Start here

Bloodwork is context—not a green light

Baseline labs can reveal existing issues and make later changes easier to interpret. They cannot prove that a protocol is safe, rule out every adverse effect, or replace symptom-based medical evaluation.

Foundation

Universal baseline

A practical starting discussion before a new protocol. Your clinician may add or remove tests based on age, sex, medications, symptoms, and medical history.

Ideally collected before starting
Core

Complete Blood Count

Red and white blood cells, hemoglobin, hematocrit, and platelets. Provides a broad hematologic baseline.

CBC with differential

Core

Metabolic Panel

Kidney function, liver-associated enzymes, electrolytes, protein, and glucose.

CMP

Metabolic

Glucose Control

Fasting glucose shows a point in time; HbA1c estimates average glycemia over roughly three months.

Fasting glucose · HbA1c

Common add-on

Lipid Panel

Total cholesterol, LDL-C, HDL-C, and triglycerides for cardiovascular and metabolic context.

Fasting may be requested

When relevant

Thyroid Panel

Useful when metabolism, fatigue, weight change, thyroid history, or GH-axis therapy makes thyroid context relevant.

TSH · Free T4; Free T3 selectively

When relevant

Inflammation

High-sensitivity CRP can provide nonspecific inflammatory context but does not identify the cause of inflammation.

hs-CRP

Match the protocol

Protocol-specific monitoring

Start with the universal baseline, then discuss the add-ons associated with the compound class. “Consider” means the marker is context-dependent—not automatically required for everyone.

Metabolic

GLP-1–based compounds

Semaglutide, tirzepatide, retatrutide, and cagrilintide-containing strategies.

Track: HbA1c, fasting glucose, CMP, and lipid panel.

Consider: Urine albumin/creatinine when diabetes or kidney risk is present.

Timing: Baseline, after titration or around 8–12 weeks, then based on response and risk.

Growth hormone axis

GH secretagogues

CJC-1295 No DAC / ipamorelin, tesamorelin, sermorelin, and related compounds.

Track: IGF-1, fasting glucose, HbA1c, and CMP.

Consider: Thyroid testing and lipid panel; cortisol or prolactin only when the compound or symptoms justify it.

Timing: Baseline and after steady use—often around 6–12 weeks.

Advanced

IGF-1 LR3 & growth compounds

Higher-uncertainty compounds need clinician oversight; routine labs do not remove their risk.

Track: Fasting glucose, HbA1c, CMP, and IGF-1 when applicable.

Consider: Fasting insulin and additional testing directed by medical history and symptoms.

Timing: Baseline and clinician-directed monitoring during use.

Recovery

Healing & immune peptides

BPC-157, TB-500, KPV, GHK-Cu, thymosin alpha-1, and similar protocols.

Track: CBC and CMP as general baseline context.

Consider: hs-CRP when inflammation is a defined target; copper status only when clinically relevant to extended copper-peptide exposure.

Timing: Baseline and repeat only when duration, symptoms, or clinical goals support it.

Longevity

Mitochondrial & longevity compounds

MOTS-c, SS-31, NAD+, Epitalon, and longevity-oriented bioregulators.

Track: CBC, CMP, fasting glucose, HbA1c, and lipid panel.

Consider: hs-CRP when systemic inflammation is a stated outcome.

Timing: Baseline and after a long enough interval to plausibly measure change.

Hormonal

Kisspeptin & reproductive goals

Hormone testing must account for sex, age, menstrual timing, medications, and the reason for testing.

Track: LH, FSH, total testosterone, and estradiol when appropriate.

Consider: Free testosterone, SHBG, prolactin, progesterone, or fertility testing based on the goal.

Timing: Standardize time of day and cycle timing when applicable.

Monitoring timeline

When to check

01

Before starting

Establish a clean baseline before the compound can influence the marker.

02

After steady exposure

Often 6–12 weeks, depending on the compound, titration schedule, marker, and clinical risk.

03

Any time symptoms change

Do not wait for a planned lab date when concerning symptoms appear. Seek medical evaluation.

Reference ranges are not universal. Results vary by laboratory method, age, sex, pregnancy status, medications, collection timing, hydration, and medical history. Use the range printed by the performing laboratory and have results interpreted by a licensed clinician. This guide is educational and is not medical advice.